Hypothalamic Sirt1 Regulates Food Intake in a Rodent Model System
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چکیده
منابع مشابه
Hypothalamic Sirt1 Regulates Food Intake in a Rodent Model System
Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of processes including cellular differentiation, apoptosis, as well as metabolism, and aging. In this study, we investigated the role of hypothalamic Sirt1 in energy balance. Pharmacological inhibition or siRNA mediated knock down of hypothalamic Sirt1 showed to decrease food intake and body weight gain. ...
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This brief review of the neural control of food intake is prepared as an introduction to this symposium and is not to be considered as a complete coverage of all the aspects of anatomy, physiology, behavioural and metabolic studies which have provided information on the influence of the hypothalamus on feeding behaviour. Readers who are interested in greater detail will find appropriate referen...
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Animals eat different amounts of different diets, which implies that they recognize some quality or qualities of the diet. Both Cowgill' and Adolph1 were aware of this problem, but no one appears to have made a systematic attempt to define the dietary quality recognized by animals. Both of these workers were led to the opinion that their animals seemed to "eat for calories," i.e., for energy. H...
متن کاملHypothalamic control of food intake
This brief review of the neural control of food intake is prepared as an introduction to this symposium and is not to be considered as a complete coverage of all the aspects of anatomy, physiology, behavioural and metabolic studies which have provided information on the influence of the hypothalamus on feeding behaviour. Readers who are interested in greater detail will find appropriate referen...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0008322